1. FAQs
  2. PreCardix®
  3. Co-administration with Medications

Can I take PreCardix® with other medication?

Consult with your primary health care provider before adding PreCardix® along-side other medications or supplements. Do not discontinue current medication without consulting with your health care provider. PreCardix® is not a substitute for medication. Monitor blood pressure regularly.

PreCardix® was not studied in combination with other medications or supplements. Interactions are inferred based on documented interactions of common ACE inhibiting drugs. Other interactions may also occur.

  • The effect of PreCardix® on blood pressure may be augmented by other blood pressure medication or natural health products and cause low blood pressure. This effect has been well-documented with individuals combining alpha-blocking medication and ACE inhibitors after the first dose. Monitor for this potential effect.
  • PreCardix® bioactive marine peptides did not increase potassium levels in the clinical trial. However, due to the ACE inhibiting action, potassium levels should be monitored frequently, particularly with agents that increase serum potassium, such as potassium-sparing diuretics, potassium supplements, and potassium-containing salts.
  • A possible causal relationship between ACE inhibitor treatments and allopurinol (a pharmaceutical treatment for gout) may lead to hypersensitivity. PreCardix® should be used cautiously with allopurinol until further research establishes safety.
  • The use of NSAIDs (such as Ibuprofen) may reduce the effect of ACE inhibiting medication. Monitor blood pressure regularly if you are taking NSAIDs with PreCardix®.
  • Intravenous iron infusion should be administered cautiously in individuals using PreCardix®. ACE inhibitors may augment the systemic effects of IV iron. Oral iron supplementation is not a concern.
  • Individuals taking lithium should have lithium levels monitored frequently. ACE inhibitors may decrease renal elimination of lithium, leading to lithium toxicity (CNS symptoms, ECG changes, renal failure). PreCardix® was not studied along-side lithium medication

Share the PreCardix® product monograph with your health care provider who can advise you on drug interactions, contra-indications and other factors related to your health to help determine if PreCardix® is appropriate for you. 

Always consult with your health care provider before making changes to your blood pressure management plan. PreCardix® does not treat, cure or prevent medical conditions.  Measure and monitor blood pressure regularly. Know the signs of heart attack and stroke. Do not take PreCardix® if you are pregnant, breastfeeding, have renal artery stenosis, history of angioneurotic edema or shellfish allergy.